Endocrine Abstracts

Introduction: Thyrotoxicosis has been shown to cause deterioration of glucose levels in patients with DM 2 while return to euthyroidism results in better glycaemic control. Studies in normal subjects suggest that increased thyroid hormones may aggravate insulin resistance and decrease pancreatic secretion of insulin but the exact underlying mechanisms have not been completely elucidated. The purpose of this study was to investigate if this also occurs in subclinical hyperthyro...

Background and aims: It is well recognized that insulin resistance and type 2 diabetes (T2DM) are associated with an increased risk for cardiovascular disease especially in women, while the role of sex steroids is still controversial. Women with polycystic ovary syndrome (PCOS) represent a unique biological model for the study of the impact of all these factors on cardiovascular system. We aimed to evaluate the degree of low-grade inflammation and atherosclerosis in premenopau...